Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.66 |
| ▸ | KEAP1 | Q14145 | 4/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.55 |
| ▸ | SQSTM1 | Q13501 | 1/20 | 0.55 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.55 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.55 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.52 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5955298 | 0.87 | FFAR4 (0.71) | FFAR4KEAP1NFE2L2SQSTM1GABRG2 | |
| SCHEMBL28597367 | 0.85 | KEAP1 (0.60) | FFAR4KEAP1NFE2L2MAPTLMNA | |
| SCHEMBL12768020 | 0.81 | FFAR4 (0.81) | FFAR4KEAP1NFE2L2SQSTM1GABRG2 | |
| SCHEMBL30958863 | 0.81 | FFAR4 (0.63) | FFAR4KEAP1NFE2L2SQSTM1GABRG2 | |
| SCHEMBL28728869 | 0.81 | FFAR4 (0.63) | FFAR4KEAP1NFE2L2SQSTM1GABRG2 | |
| SCHEMBL19364119 | 0.81 | GAA (0.64) | FFAR4KEAP1NFE2L2SQSTM1GABRG2 | |
| SCHEMBL23200363 | 0.80 | FFAR4 (0.65) | FFAR4KEAP1MAPTLMNAKMT2A | |
| SCHEMBL31138312 | 0.80 | FFAR4 (0.65) | FFAR4KEAP1MAPTLMNAKMT2A | |
| SCHEMBL28534702 | 0.80 | FFAR4 (0.61) | FFAR4KEAP1NFE2L2SQSTM1GABRG2 | |
| SCHEMBL29083801 | 0.80 | FFAR4 (0.61) | FFAR4KEAP1NFE2L2SQSTM1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113173877-B | Indole acetyl imino sulfone series compounds and preparation method thereof | 江西师范大学 | 2023-10-27 | — | — | CN | disclosed |
| CN-113173877-A | Indole acetyl imino sulfone series compound and preparation method thereof | 江西师范大学 | 2021-07-27 | — | — | CN | disclosed |