Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17386084 | 0.76 | CA1 (0.45) | CA1CA2TDP1MAPTMMP1 | |
| SCHEMBL18828099 | 0.74 | CA1 (0.46) | CA1CA2TDP1MAPTMMP1 | |
| SCHEMBL17386226 | 0.71 | CA1 (0.53) | CA1CA2TDP1MAPTKMT2A | |
| SCHEMBL1663286 | 0.71 | CA1 (0.58) | CA1CA2TDP1MAPTKMT2A | |
| SCHEMBL988746 | 0.70 | CA1 (0.53) | CA1CA2TDP1KMT2AMEN1 | |
| SCHEMBL25335887 | 0.70 | MAPT (0.50) | CA1CA2TDP1MAPTKMT2A | |
| SCHEMBL17386315 | 0.69 | MAPT (0.57) | CA1CA2TDP1MAPTKMT2A | |
| SCHEMBL17386317 | 0.69 | MAPT (0.57) | CA1CA2TDP1MAPTKMT2A | |
| SCHEMBL31173883 | 0.68 | MAPT (0.49) | CA1CA2TDP1MAPTKMT2A | |
| SCHEMBL11351348 | 0.68 | CA1 (0.50) | CA1CA2TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108017603-B | Tricyclic compounds and uses thereof | 株式会社蒂奥姆生物 | 2021-07-23 | — | — | CN | disclosed |