Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 7/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL887259 | 0.92 | THRB (0.37) | TSHRALDH1A1CA1CA2THRB | |
| SCHEMBL11615338 | 0.89 | THRB (0.42) | TSHRALDH1A1CA1CA2THRB | |
| SCHEMBL11310968 | 0.89 | THRB (0.42) | TSHRALDH1A1CA1CA2THRB | |
| SCHEMBL9329861 | 0.89 | THRB (0.42) | TSHRALDH1A1CA1CA2THRB | |
| SCHEMBL9329817 | 0.89 | THRB (0.42) | TSHRALDH1A1CA1CA2THRB | |
| 1,4-Butanediol SCHEMBL11789543 | 0.88 | SMN1; SMN2 (0.48) | ADRB2ADRB1ADRB3TSHRALDH1A1 | |
| SCHEMBL3899062 | 0.85 | — | — | |
| SCHEMBL2863621 | 0.81 | — | — | |
| SCHEMBL11442686 | 0.80 | — | — | |
| SCHEMBL10405812 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116348448-A | Scalable synthetic routes to siloxine and silodosin | 明德赛特制药公司 | 2023-06-27 | — | — | CN | claimed |
| US-8453425-B2 | Soot reduction by combustor conditioning | LOCKHEED MARTIN CORPORATION (US) | 2013-06-04 | — | — | US | claimed |
| US-20100186387-A1 | Soot Reduction By Combustor Conditioning | GENERAL ELECTRIC COMPANY | 2010-07-29 | — | — | US | claimed |
| US-4242479-A | CATALYST OF ALUMINUM TRIHALIDE, ORGANOSILOXANE COMPOUND OR ETHER, MAGNESIUM ALCOHOLATE, TITANIUM-HALOGEN AND ORGANOALUMINUM COMPOUNDS | SHOWA YUKA KABUSHIKI KAISHA (JP) | 1980-12-30 | — | — | US | claimed |
| CN-112028936-A | Purification method of methyl phosphonous acid dialkyl ester | 河北威远生物化工有限公司 | 2020-12-04 | — | — | CN | disclosed |
| US-8453425-B2 | Soot reduction by combustor conditioning | LOCKHEED MARTIN CORPORATION (US) | 2013-06-04 | — | — | US | disclosed |
| US-20100186387-A1 | Soot Reduction By Combustor Conditioning | GENERAL ELECTRIC COMPANY | 2010-07-29 | — | — | US | disclosed |
| EP-1318156-B1 | Novel asymmetric phosphine ligand | TAKASAGO PERFUMERY CO LTD (JP) | 2010-01-20 | — | — | EP | disclosed |
| EP-1318155-B1 | Novel asymmetric phosphine ligand | TAKASAGO PERFUMERY CO LTD (JP) | 2005-03-23 | — | — | EP | disclosed |
| US-6730629-B2 | HYDROGENATION CATALYST | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2004-05-04 | — | — | US | disclosed |
| US-6624320-B2 | Phosphorane compound hydrogenation catalyts; stereospecific; catalyst selectivity | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2003-09-23 | — | — | US | disclosed |
| US-20030144138-A1 | NOVEL ASYMMETRIC PHOSPHINE LIGAND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2003-07-31 | — | — | US | disclosed |
| US-4242479-A | CATALYST OF ALUMINUM TRIHALIDE, ORGANOSILOXANE COMPOUND OR ETHER, MAGNESIUM ALCOHOLATE, TITANIUM-HALOGEN AND ORGANOALUMINUM COMPOUNDS | SHOWA YUKA KABUSHIKI KAISHA (JP) | 1980-12-30 | — | — | US | disclosed |
| US-4237075-A | Formamide catalysts for reacting phosphorus halides with thiols | MOBIL OIL CORPORATION (US) | 1980-12-02 | — | — | US | disclosed |
| US-4222930-A | VULCANIZABLE RUBBER, SILICEOUS FILLER | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1980-09-16 | — | — | US | disclosed |
| US-4187385-A | TITANIUM COMPONENT COPULVERIZED WITH ORGANOALUMINUM COMPOUND AND ETHYLENE OR A-OLEFINS, PARTICLE SIZE | MITSUI TOATSU CHEMICAL, INC. (JP) | 1980-02-05 | — | — | US | disclosed |
| US-4152347-A | REINFORCING AGENTS IN VULCANIZABLE RUBBER MIXTURES WHICH CONTAIN A SILICA FILLER | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1979-05-01 | — | — | US | disclosed |
| US-4079103-A | Process for the production of phosphite chlorides | CIBA-GEIGY CORPORATION (US) | 1978-03-14 | — | — | US | disclosed |
| US-4032602-A | PROCESS FOR THE PRODUCTION OF PHOSPHITE CHLORIDES | CIBA-GEIGY CORPORATION (US) | 1977-06-28 | — | — | US | disclosed |
| US-4028481-A | ACTIVATED TITANIUM TRICHLORIDE AND AN ORGANOALUMINUM COMPOUND | MITSUI TOATSU CHEMICALS, INCORPORATED (JA) | 1977-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144138-A1 | NOVEL ASYMMETRIC PHOSPHINE LIGAND | PHOSPHO1, PLCG2, PLCB3 | ADRB2 775/4885ADRB1 1110/4885ADRB3 1970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.