Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.45 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | OGA | O60502 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28614883 | 0.75 | PDE4D (0.47) | KMT2AMEN1LMNAL3MBTL1MAPK1 | |
| SCHEMBL28601409 | 0.73 | SMN1; SMN2 (0.44) | KMT2AKDM4ELMNAMAPK1HTT | |
| SCHEMBL28603795 | 0.73 | JAK2 (0.48) | S100A4KMT2AMEN1 | |
| SCHEMBL30173300 | 0.73 | JAK2 (0.48) | S100A4KMT2AMEN1 | |
| SCHEMBL28603778 | 0.71 | HTR2C (0.46) | KMT2AMEN1 | |
| SCHEMBL14671602 | 0.67 | KMT2A (0.54) | S100A4KMT2AMEN1KDM4ELMNA | |
| SCHEMBL14135859 | 0.66 | S100A4 (0.63) | S100A4HCRTR1HCRTR2KMT2AMEN1 | |
| SCHEMBL16252993 | 0.66 | KMT2A (0.53) | S100A4HCRTR1HCRTR2KMT2AMEN1 | |
| SCHEMBL16803495 | 0.65 | KMT2A (0.57) | S100A4HCRTR1HCRTR2KMT2AMEN1 | |
| SCHEMBL3243299 | 0.64 | SMN1; SMN2 (0.49) | HCRTR1HCRTR2KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113200983-A | Compound with pyrrolopyridine structure, preparation method and medical application | 中国药科大学 | 2021-08-03 | — | — | CN | disclosed |