SCHEMBL28598909

SCHEMBL28598909

CCCCCCc1ccc(-c2ccsc2C=O)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 7/20 0.46
ALDH1A1 P00352 2/20 0.46
MEN1 O00255 1/20 0.46
RARA P10276 1/20 0.46
MAPT P10636 1/20 0.46
MTOR P42345 1/20 0.46
KMT2A Q03164 1/20 0.46
HSD17B10 Q99714 2/20 0.43
TSHR P16473 1/20 0.43
ESR1 P03372 2/20 0.42
ADRA2A P08913 2/20 0.42
ADORA3 P0DMS8 2/20 0.42
TACR2 P21452 2/20 0.42
SLC6A2 P23975 2/20 0.42
SLC6A4 P31645 2/20 0.42
SLC6A3 Q01959 2/20 0.42
KDM4E B2RXH2 1/20 0.42
LMNA P02545 1/20 0.42
SHBG P04278 1/20 0.42
TP53 P04637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13766280 0.82 EDNRB (0.38) ALDH1A1MEN1MAPTKMT2ALMNA
SCHEMBL28258613 0.79 PTGS1 (0.50) RARBALDH1A1MEN1RARAMAPT
SCHEMBL3466328 0.78 HSD17B10 (0.46) RARBALDH1A1MEN1RARAMAPT
SCHEMBL12270309 0.77 RARB (0.46) RARBALDH1A1MEN1RARAMAPT
SCHEMBL28598911 0.76 NR1H2 (0.45)
SCHEMBL2146038 0.75 HIF1A (0.42) MEN1MAPTKMT2AHSD17B10TSHR
SCHEMBL18826026 0.75 HIF1A (0.42) MEN1MAPTKMT2AHSD17B10TSHR
SCHEMBL820018 0.75 HIF1A (0.42) MEN1MAPTKMT2AHSD17B10TSHR
SCHEMBL18826032 0.75 HIF1A (0.42) MEN1MAPTKMT2AHSD17B10TSHR
SCHEMBL371668 0.75 HIF1A (0.42) MEN1MAPTKMT2AHSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119528876-A Substituent modified oxo benzene core non-condensed ring small molecule, preparation method thereof and photoelectric device application 武汉工程大学 2025-02-28 CN disclosed
CN-113072533-B Non-condensed electron acceptor material and organic solar cell constructed by same 浙江大学 2023-10-31 CN disclosed
CN-113072533-A Non-condensed electron acceptor material and organic solar cell constructed by same 浙江大学 2021-07-06 CN disclosed