Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | P2RY10 | O00398 | 8/20 | 0.35 |
| ▸ | GPR34 | Q9UPC5 | 5/20 | 0.35 |
| ▸ | GPR174 | Q9BXC1 | 5/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTGFR | P43088 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28599255 | 1.00 | AKR1C3 (0.40) | AKR1C3AKR1C2P2RY10GPR34GPR174 | |
| SCHEMBL21647725 | 0.76 | ADRB2 (0.44) | P2RY10GPR34GPR174PPARDADRB2 | |
| SCHEMBL21647771 | 0.74 | PPARD (0.40) | P2RY10GPR34GPR174PPARDADRB2 | |
| SCHEMBL29483750 | 0.70 | ADRB2 (0.39) | P2RY10GPR34GPR174PPARDKDM4E | |
| SCHEMBL21647798 | 0.70 | ADRB2 (0.39) | P2RY10GPR34GPR174PPARDKDM4E | |
| SCHEMBL31548939 | 0.70 | HDAC3 (0.43) | ADRB2ADRB1 | |
| SCHEMBL28612714 | 0.70 | HDAC3 (0.43) | ADRB2ADRB1 | |
| SCHEMBL28604448 | 0.70 | HDAC3 (0.43) | ADRB2ADRB1 | |
| SCHEMBL21647708 | 0.70 | HDAC3 (0.43) | ADRB2ADRB1 | |
| SCHEMBL29483739 | 0.69 | KDM4E (0.36) | P2RY10GPR34GPR174PPARDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513011-B | Benzene derivatives | 小野药品工业株式会社 | 2023-06-16 | — | — | CN | disclosed |
| CN-112513011-A | Benzene derivatives | 小野药品工业株式会社 | 2021-03-16 | — | — | CN | disclosed |