SCHEMBL28599276

SCHEMBL28599276

Nc1cc(C(=O)c2ccccc2)c(Oc2ccccc2)c(Oc2ccccc2)c1N

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.49
GAA P10253 1/20 0.49
LMNA P02545 2/20 0.47
MEN1 O00255 1/20 0.47
USP2 O75604 1/20 0.47
ALDH1A1 P00352 1/20 0.47
GLA P06280 1/20 0.47
KMT2A Q03164 1/20 0.47
HSD17B10 Q99714 1/20 0.47
POLB P06746 2/20 0.46
CCNE2 O96020 1/20 0.44
CCNE1 P24864 1/20 0.44
CDK2 P24941 1/20 0.44
SRD5A2 P31213 2/20 0.42
AKR1C3 P42330 1/20 0.42
MAPK1 P28482 2/20 0.42
MAPK14 Q16539 1/20 0.40
TSHR P16473 1/20 0.40
HTT P42858 1/20 0.40
ADORA1 P30542 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28340608 0.88 MAPT (0.49) MAPTGAALMNAMEN1USP2
SCHEMBL27907622 0.83 MAPT (0.44) MAPTGAALMNAMEN1USP2
SCHEMBL21808151 0.81 MAPT (0.51) MAPTGAALMNAMEN1USP2
SCHEMBL28359611 0.80 MAPT (0.44) MAPTGAALMNAMEN1USP2
SCHEMBL29363979 0.80 POLB (0.51) MAPTGAALMNAMEN1USP2
SCHEMBL28346594 0.80 POLB (0.51) MAPTGAALMNAMEN1USP2
SCHEMBL27737105 0.78 MAPT (0.61) MAPTGAALMNAMEN1USP2
SCHEMBL26135851 0.78 POLB (0.45) MAPTGAALMNAMEN1USP2
SCHEMBL27956981 0.78 CTNNB1 (0.44) MAPTGAALMNAMEN1USP2
SCHEMBL9063955 0.76 POLB (0.50) MAPTGAALMNAMEN1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113950409-B Laminate body 东洋纺株式会社 2024-06-28 CN disclosed
CN-117836134-A Laminate body 东洋纺株式会社 2024-04-05 CN disclosed
CN-117642286-A Laminate roll 东洋纺株式会社 2024-03-01 CN disclosed
CN-116940420-A Method for producing resin film and film before cutting 东洋纺株式会社 2023-10-24 CN disclosed
CN-113518792-B Polybenzoxazole precursor containing ester diamine, photosensitive resin composition, dry film, cured product, and electronic component 太阳控股株式会社 2023-08-15 CN disclosed
CN-116075421-A Laminate, method for producing laminate, and method for producing flexible electronic device 东洋纺株式会社 2023-05-05 CN disclosed
CN-115667379-A Resin film and method for producing resin film 东洋纺株式会社 2023-01-31 CN disclosed
CN-115551714-A Laminate comprising transparent highly heat-resistant film 东洋纺株式会社 2022-12-30 CN disclosed
CN-115515790-A Colorless multilayer polyimide film, laminate, and method for manufacturing flexible electronic device 东洋纺株式会社 2022-12-23 CN disclosed
CN-115461221-A Polyimide film and method for producing same 东洋纺株式会社 2022-12-09 CN disclosed
CN-110249376-B Optical film and image display device 大日本印刷株式会社 2021-08-24 CN disclosed
CN-109844847-B Optical film and image display device 大日本印刷株式会社 2021-07-13 CN disclosed