Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | FAAH | O00519 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | CCR3 | P51677 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | CA9 | Q16790 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4414755 | 0.92 | KDM4E (0.69) | KDM4ELMNAL3MBTL1ALDH1A1FAAH | |
| SCHEMBL4578765 | 0.91 | MEN1 (0.70) | KDM4ELMNAL3MBTL1ALDH1A1FAAH | |
| SCHEMBL4577307 | 0.90 | KDM4E (0.67) | KDM4ELMNAL3MBTL1ALDH1A1FAAH | |
| Hydrochloric Acid SCHEMBL4577724 | 0.90 | KDM4E (0.67) | KDM4ELMNAL3MBTL1ALDH1A1FAAH | |
| SCHEMBL4578859 | 0.89 | ALDH1A1 (0.67) | KDM4ELMNAL3MBTL1ALDH1A1FAAH | |
| Hydrochloric Acid SCHEMBL4578881 | 0.89 | KDM4E (0.66) | KDM4ELMNAL3MBTL1ALDH1A1FAAH | |
| Hydrochloric Acid SCHEMBL4576674 | 0.88 | ALDH1A1 (0.66) | KDM4ELMNAL3MBTL1ALDH1A1FAAH | |
| SCHEMBL13490093 | 0.88 | ALDH1A1 (0.66) | KDM4ELMNAL3MBTL1ALDH1A1FAAH | |
| SCHEMBL4578306 | 0.88 | KDM4E (0.64) | KDM4ELMNAL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL4576852 | 0.88 | SMN1; SMN2 (0.72) | KDM4ELMNAL3MBTL1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113214140-B | Piperidine amide derivative, pharmaceutical composition and application thereof | 江苏谛奇医药科技有限公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-113214139-B | Piperidine amide derivative, preparation method thereof, pharmaceutical composition thereof, single crystal culture method thereof and application thereof | 江苏谛奇医药科技有限公司 | 2022-03-04 | — | — | CN | disclosed |
| CN-113214140-A | Piperidine amide derivative, pharmaceutical composition and application thereof | 江苏谛奇医药科技有限公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-113214139-A | Piperidine amide derivative, preparation method thereof, pharmaceutical composition thereof, single crystal culture method thereof and application thereof | 江苏谛奇医药科技有限公司 | 2021-08-06 | — | — | CN | disclosed |