Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 10/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 4/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28599432 | 1.00 | SCN9A (0.36) | SCN9ACYP3A4KDM4EHCRTR2HTT | |
| SCHEMBL14163632 | 0.82 | BACE1 (0.39) | SCN9AHTTALDH1A1HPGD | |
| SCHEMBL28588751 | 0.82 | ATM (0.43) | CYP3A4ALDH1A1 | |
| SCHEMBL28588750 | 0.82 | ATM (0.43) | CYP3A4ALDH1A1 | |
| SCHEMBL13725768 | 0.81 | HCRTR2 (0.40) | HCRTR2 | |
| SCHEMBL28588817 | 0.81 | HCRTR2 (0.40) | HCRTR2 | |
| SCHEMBL28575650 | 0.80 | HCRTR2 (0.37) | HCRTR2HCRTR1 | |
| SCHEMBL28580336 | 0.79 | HCRTR2 (0.39) | HCRTR2 | |
| SCHEMBL28580334 | 0.79 | HCRTR2 (0.39) | HCRTR2 | |
| SCHEMBL20263097 | 0.78 | HCRTR2 (0.35) | SCN9ACYP3A4HCRTR2HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107709301-B | Pyrazole derivative or pharmacologically acceptable salt thereof | 橘生药品工业株式会社 | 2021-06-22 | — | — | CN | disclosed |