Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ACP3 | P15309 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8405089 | 0.80 | ALDH1A1 (0.43) | TSHRLMNAMAPTALDH1A1ACHE | |
| SCHEMBL6970435 | 0.79 | TSHR (0.52) | TSHRLMNAACP3SMN1; SMN2MAPT | |
| SCHEMBL2191814 | 0.75 | ALDH1A1 (0.48) | TSHRLMNAACP3SMN1; SMN2MAPT | |
| SCHEMBL4093002 | 0.75 | TSHR (0.67) | TSHRLMNAACP3SMN1; SMN2MAPT | |
| SCHEMBL28459256 | 0.75 | TSHR (0.55) | TSHRLMNAACP3SMN1; SMN2MAPT | |
| SCHEMBL6689743 | 0.73 | ACP3 (0.46) | TSHRLMNAACP3SMN1; SMN2ALDH1A1 | |
| SCHEMBL254876 | 0.72 | TSHR (0.61) | TSHRLMNAACP3SMN1; SMN2MAPT | |
| SCHEMBL3642758 | 0.72 | TSHR (0.61) | TSHRLMNAACP3SMN1; SMN2MAPT | |
| SCHEMBL11432821 | 0.72 | TSHR (0.61) | TSHRLMNAACP3SMN1; SMN2MAPT | |
| SCHEMBL384083 | 0.72 | TSHR (0.61) | TSHRLMNAACP3SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109096212-B | Method for synthesizing 5-I-1,2, 3-triazole compound by water phase one-pot method | 河南师范大学 | 2021-07-13 | — | — | CN | disclosed |