SCHEMBL2860001

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2467474	0.88	ALDH1A1 (0.47)	ADORA2AADORA1ABCG2TDP1ALDH1A1
	SCHEMBL2469222	0.88	ADORA2A (0.38)	ADORA2APTGER1ADORA1ABCG2TDP1
	SCHEMBL2872658	0.85	ADORA2A (0.41)	ADORA2APTGER1TAAR1ADORA1ADORA2B
	SCHEMBL27536115	0.83	ALDH1A1 (0.41)	PTGER1ABCG2ALDH1A1LMNANPSR1
	SCHEMBL2861558	0.83	PTGER1 (0.39)	ADORA2APTGER1ADORA1DPP4ALDH1A1
	SCHEMBL2861890	0.83	PTGER1 (0.37)	ADORA2APTGER1TAAR1ADORA1DPP4
	SCHEMBL2857935	0.82	ADORA2A (0.41)	ADORA2APTGER1TAAR1ADORA1ADORA2B
	SCHEMBL173515	0.81	PTGER1 (0.38)	ADORA2APTGER1ADORA1TDP1ALDH1A1
	SCHEMBL30084116	0.81	PTGER1 (0.38)	ADORA2APTGER1ADORA1TDP1ALDH1A1
	SCHEMBL4136387	0.81	CSNK2A2 (0.41)	ADORA2APTGER1ADORA1ADORA2BABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.