SCHEMBL28600071

SCHEMBL28600071

O=Cc1c(OCC2CC2)cc(O)c(Cl)c1F

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 13/20 0.37
SIRT1 Q96EB6 1/20 0.36
FFAR4 Q5NUL3 1/20 0.35
CNR2 P34972 1/20 0.34
KMO O15229 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28583863 0.96 SCN9A (0.41) SCN9A
SCHEMBL23360988 0.80 ALDH1A1 (0.45)
SCHEMBL28583768 0.78
SCHEMBL28573364 0.78 MAPT (0.36) CNR2
SCHEMBL29933113 0.78 MAPT (0.36) CNR2
SCHEMBL23361148 0.75 ERN1 (0.51)
SCHEMBL28892599 0.73 HTR2C (0.38) FFAR4
SCHEMBL29945096 0.73 DRD1 (0.32)
SCHEMBL28863821 0.73 DRD1 (0.32)
SCHEMBL28581332 0.71 CYP1A2 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112812113-B Immunomodulatory compounds, compositions and uses thereof 杭州和正医药有限公司 2022-09-20 CN disclosed
CN-112812113-A Immunomodulatory compounds, compositions and uses thereof 杭州和正医药有限公司 2021-05-18 CN disclosed