SCHEMBL28600445

SCHEMBL28600445

CC(c1ccccc1)C(C)(O)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.42
CYP1A2 P05177 1/20 0.42
SLC6A4 P31645 1/20 0.41
ALDH1A1 P00352 4/20 0.40
ALOX15 P16050 1/20 0.40
CYP2C19 P33261 1/20 0.40
HSD17B10 Q99714 1/20 0.40
RIPK1 Q13546 2/20 0.39
ESR1 P03372 2/20 0.39
ESR2 Q92731 2/20 0.39
ADRA2A P08913 1/20 0.39
ADRA2C P18825 1/20 0.39
CYP3A4 P08684 1/20 0.39
LMNA P02545 1/20 0.39
HIF1A Q16665 1/20 0.39
KDM4E B2RXH2 1/20 0.39
MAPK1 P28482 1/20 0.38
CNR1 P21554 1/20 0.38
CNR2 P34972 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28024684 0.81 CYP2D6 (0.46) CYP2D6CYP1A2ALDH1A1CYP2C19HSD17B10
SCHEMBL13339074 0.80 ALDH1A1 (0.50) CYP2D6CYP1A2SLC6A4ALDH1A1CYP2C19
SCHEMBL4489962 0.80 CYP2D6 (0.41) CYP2D6CYP1A2SLC6A4ALDH1A1ALOX15
SCHEMBL2238856 0.80 ALDH1A1 (0.50) CYP2D6CYP1A2SLC6A4ALDH1A1CYP2C19
SCHEMBL28365356 0.79 ALDH1A1 (0.44) CYP2D6CYP1A2SLC6A4ALDH1A1ALOX15
SCHEMBL3959121 0.79 CYP2D6 (0.47) CYP2D6CYP1A2ALDH1A1ALOX15CYP2C19
SCHEMBL12884227 0.79 CYP2D6 (0.47) CYP2D6CYP1A2ALDH1A1ALOX15CYP2C19
SCHEMBL487167 0.79 CYP3A4 (0.47) CYP2D6CYP1A2ALDH1A1ALOX15CYP2C19
SCHEMBL1471159 0.79 SLC6A4 (0.45) CYP2D6SLC6A4ALDH1A1ALOX15CYP2C19
SCHEMBL12574668 0.79 SLC6A4 (0.45) CYP2D6SLC6A4ALDH1A1ALOX15CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110230071-B Method for preparing beta-halogenated carbonyl compound by using high-salinity wastewater 上海交通大学 2021-07-13 CN disclosed