Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5045890 | 0.94 | ALDH1A1 (0.37) | TSHRALDH1A1HSD17B10TDP1LMNA | |
| Ethylene Glycol SCHEMBL27759290 | 0.92 | TSHR (0.39) | TSHRALDH1A1 | |
| Propionic Acid SCHEMBL9448801 | 0.88 | FFAR3 (0.40) | TSHRALDH1A1HSD17B10TDP1LMNA | |
| Vinyl Chloride SCHEMBL11353157 | 0.88 | TSHR (0.33) | TSHRALDH1A1HSD17B10TDP1LMNA | |
| Ethylene Glycol SCHEMBL1423158 | 0.87 | ALDH1A1 (0.36) | TSHRALDH1A1HSD17B10TDP1LMNA | |
| Propionic Acid SCHEMBL28961502 | 0.86 | FFAR3 (0.42) | TSHRALDH1A1HSD17B10TDP1LMNA | |
| 1,6-Hexanediol SCHEMBL28324013 | 0.86 | TSHR (0.39) | TSHRALDH1A1HSD17B10LMNA | |
| Alcohol SCHEMBL7595677 | 0.85 | TSHR (0.40) | TSHRALDH1A1TDP1 | |
| Ethylene Glycol SCHEMBL28168875 | 0.85 | ALDH1A1 (0.35) | TSHRALDH1A1HSD17B10TDP1LMNA | |
| SCHEMBL15133 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112955130-A | Solid dispersions and pharmaceutical compositions comprising substituted indanes and methods of making and using the same | 佩洛通治疗公司 | 2021-06-11 | — | — | CN | disclosed |