Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | XDH | P47989 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28593396 | 0.85 | CHRM2 (0.39) | KDM4ELMNAXDHTDP1POLB | |
| SCHEMBL28327617 | 0.79 | CHRM2 (0.44) | KDM4ELMNAXDHTDP1POLB | |
| SCHEMBL4463908 | 0.79 | CHRM2 (0.47) | KDM4ELMNAXDHTDP1POLB | |
| SCHEMBL28327620 | 0.79 | LMNA (0.42) | KDM4ELMNAXDHTDP1POLB | |
| SCHEMBL6349733 | 0.76 | CHRM2 (0.41) | KDM4ELMNAXDHTDP1POLB | |
| SCHEMBL28328897 | 0.73 | ZDHHC7 (0.45) | KDM4ELMNAL3MBTL1CHRM2CHRM4 | |
| SCHEMBL363238 | 0.73 | CA1 (0.45) | KDM4ELMNAXDHTDP1POLB | |
| SCHEMBL110811 | 0.71 | NPC1 (0.53) | KDM4ELMNAXDHTDP1POLB | |
| SCHEMBL69256 | 0.71 | CA1 (0.47) | KDM4ELMNAXDHTDP1POLB | |
| SCHEMBL4471355 | 0.70 | CA12 (0.42) | KDM4ELMNAXDHTDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110305143-B | Furan [2,3-c ] pyridine derivative and preparation method and application thereof | 济南新科医药科技有限公司 | 2021-03-09 | — | — | CN | disclosed |