Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30434501 | 1.00 | TDP1 (0.58) | TDP1POLBMAPTTP53MEN1 | |
| SCHEMBL29064889 | 0.90 | TDP1 (0.48) | TDP1POLBMAPTTP53MEN1 | |
| SCHEMBL22072298 | 0.85 | TDP1 (0.54) | TDP1POLBMAPTTP53MEN1 | |
| SCHEMBL28848082 | 0.84 | KDM4E (0.60) | TDP1POLBMAPTTP53MEN1 | |
| SCHEMBL22072296 | 0.83 | TDP1 (0.62) | TDP1POLBMAPTTP53MEN1 | |
| SCHEMBL30500763 | 0.83 | TDP1 (0.62) | TDP1POLBMAPTTP53MEN1 | |
| SCHEMBL30508519 | 0.82 | MEN1 (0.55) | TDP1POLBMAPTTP53MEN1 | |
| SCHEMBL29064902 | 0.82 | MEN1 (0.55) | TDP1POLBMAPTTP53MEN1 | |
| SCHEMBL28591256 | 0.82 | TDP1 (0.51) | TDP1POLBMAPTTP53MEN1 | |
| SCHEMBL29152858 | 0.81 | SLC40A1 (0.70) | TDP1POLBMAPTTP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116478202-A | Method for synthesizing 1, 2-boron alkyne compound | 南京工业大学 | 2023-07-25 | — | — | CN | claimed |
| CN-116751160-A | Preparation method of delta-aryl-gamma-amino acid derivative | 广东工业大学 | 2023-09-15 | — | — | CN | disclosed |
| CN-116478202-A | Method for synthesizing 1, 2-boron alkyne compound | 南京工业大学 | 2023-07-25 | — | — | CN | disclosed |
| CN-116178257-A | Preparation method of delta-aryl-gamma-amino acid derivative | 广东工业大学 | 2023-05-30 | — | — | CN | disclosed |
| CN-113121432-A | Synthesis method of aliphatic alkene with guide group | 南京工业大学 | 2021-07-16 | — | — | CN | disclosed |