Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28601361 | 0.81 | SMN1; SMN2 (0.49) | ALDH1A1SMN1; SMN2MAPTHTTGAA | |
| SCHEMBL19672580 | 0.76 | SMN1; SMN2 (0.56) | ALDH1A1SMN1; SMN2MAPTHTTGAA | |
| SCHEMBL14549411 | 0.72 | SMN1; SMN2 (0.48) | ALDH1A1SMN1; SMN2MAPTHTTGAA | |
| SCHEMBL28601433 | 0.69 | POLB (0.57) | ALDH1A1SMN1; SMN2MAPTHTTGAA | |
| SCHEMBL15880406 | 0.69 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2MAPTHTTGAA | |
| SCHEMBL6141396 | 0.68 | POLB (0.68) | ALDH1A1SMN1; SMN2MAPTHTTGAA | |
| SCHEMBL28605540 | 0.68 | MAPT (0.42) | ALDH1A1SMN1; SMN2MAPTHTTGAA | |
| SCHEMBL14612413 | 0.67 | POLB (0.66) | ALDH1A1SMN1; SMN2MAPTHTTGAA | |
| SCHEMBL84337 | 0.67 | POLB (0.66) | ALDH1A1SMN1; SMN2MAPTHTTGAA | |
| SCHEMBL3524765 | 0.67 | POLB (0.66) | ALDH1A1SMN1; SMN2MAPTHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113024430-A | Process for converting substituted arylamines to arylazomethylsulfones | 天津师范大学 | 2021-06-25 | — | — | CN | disclosed |