Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 7/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL609522 | 0.87 | LMNA (0.57) | POLBALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6141396 | 0.85 | POLB (0.68) | POLBALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL84337 | 0.83 | POLB (0.66) | POLBALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL14612413 | 0.83 | POLB (0.66) | POLBALDH1A1SMN1; SMN2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL27712068 | 0.82 | POLB (0.64) | POLBALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL1094692 | 0.81 | POLB (0.44) | POLBALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL11147117 | 0.81 | POLB (0.44) | POLBALDH1A1NPC1RAB9APKM | |
| SCHEMBL25213930 | 0.80 | ALDH1A1 (0.57) | POLBALDH1A1SMN1; SMN2RAB9APKM | |
| SCHEMBL30991708 | 0.80 | ALDH1A1 (0.57) | POLBALDH1A1SMN1; SMN2RAB9APKM | |
| SCHEMBL6647659 | 0.80 | POLB (1.00) | POLBALDH1A1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108610301-B | Chiral aromatic heterocyclic amine derivative and synthesis method and application thereof | 中山大学 | 2021-08-31 | — | — | CN | disclosed |
| CN-108610301-A | A kind of chiral fragrant miscellaneous amine derivant and its synthetic method and application | 中山大学 | 2018-10-02 | — | — | CN | disclosed |
| US-9850382-B1 | Unsymmetrical cyanine dyes and their application | Ying, Laiqiang (US) | 2017-12-26 | — | — | US | disclosed |
| US-8436040-B2 | Method of treating conditions involving PPAR-receptors with indole compounds | LABORATOIRES FOURNIER S.A. (FR) | 2013-05-07 | — | — | US | disclosed |
| CN-101242833-B | Pyrrolopyridine derivatives and use of same as PPAR receptor modulators | FOURNIER LAB SA | 2012-06-27 | — | — | CN | disclosed |
| US-20100286137-A1 | Method of Treating Conditions Involving PPAR-Receptors with Indole Compounds | LABORATORIES FOURNIER S.A. (FR) | 2010-11-11 | — | — | US | disclosed |
| US-7795297-B2 | Indole compounds, method of preparing them and uses thereof | LABORATORIES FOURNIER S.A. (FR) | 2010-09-14 | — | — | US | disclosed |
| US-7728002-B2 | Use of pyrrolopyridine compounds for activating PPAR receptors and treatment of conditions involving such receptors | LABORATOIRES FOURNIER S.A. (FR) | 2010-06-01 | — | — | US | disclosed |
| US-20090239856-A1 | Use of Pyrrolopyridine Compounds for Activating PPAR Receptors and Treatment of Conditions Involving Such Receptors | LABORATOIRES FOURNIER S.A. (FR) | 2009-09-24 | — | — | US | disclosed |
| US-7557122-B2 | Pyrrolopyridine compounds, method of making them and uses thereof | LABORATOIRES FOURNIER S.A. (FR) | 2009-07-07 | — | — | US | disclosed |
| US-20080200495-A1 | Pyrrolopyridine Compounds, Method of Making Them and Uses Thereof | LABORATOIRES FOURNIER S.A. (FR) | 2008-08-21 | — | — | US | disclosed |
| CN-101242833-A | Pyrrolopyridine derivatives and use of same as PPAR receptor modulators | FOURNIER LAB SA (FR) | 2008-08-13 | — | — | CN | disclosed |
| US-20080153816-A1 | Indole Compounds, Method of Preparing Them and Uses Thereof | LABORATOIRES FOURNIER S.A. (FR) | 2008-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239856-A1 | Use of Pyrrolopyridine Compounds for Activating PPAR Receptors and Treatment of Conditions Involving Such Receptors | PPARD, PPARA, PPARG | POLB 1219/4885ALDH1A1 1314/4885SMN1; SMN2 3212/4885 |
| US-20080200495-A1 | Pyrrolopyridine Compounds, Method of Making Them and Uses Thereof | LIPG, PCSK9, PNLIP | POLB 1293/4885ALDH1A1 1350/4885SMN1; SMN2 2484/4885 |
| US-20080153816-A1 | Indole Compounds, Method of Preparing Them and Uses Thereof | LIPG, GPR119, IAPP | POLB 4410/4885ALDH1A1 1607/4885SMN1; SMN2 2892/4885 |
| US-20100286137-A1 | Method of Treating Conditions Involving PPAR-Receptors with Indole Compounds | GPR119, PPARA, PPARG | POLB 3181/4885ALDH1A1 1453/4885SMN1; SMN2 3475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.