Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | GCK | P35557 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 7/20 | 0.38 |
| ▸ | BRAF | P15056 | 3/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.37 |
| ▸ | PYGL | P06737 | 1/20 | 0.37 |
| ▸ | PYGM | P11217 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4334289 | 0.90 | KMT2A (0.54) | KMT2AMEN1PKMALDH1A1MAPT | |
| SCHEMBL28917671 | 0.86 | KDR (0.42) | GCKKDRBRAF | |
| SCHEMBL4322907 | 0.85 | ALDH1A1 (0.48) | KMT2AMEN1PKMALDH1A1MAPT | |
| SCHEMBL4329875 | 0.84 | KDR (0.46) | KMT2AMEN1PKMALDH1A1MAPT | |
| SCHEMBL4329326 | 0.81 | KDR (0.46) | KMT2AMEN1PKMALDH1A1MAPT | |
| SCHEMBL28593422 | 0.80 | GCK (0.47) | ALDH1A1MAPTGCKKDRBRAF | |
| SCHEMBL13860977 | 0.78 | AXL (0.52) | KMT2AALDH1A1MAPTLMNAGCK | |
| SCHEMBL200277 | 0.77 | AXL (0.50) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL29251625 | 0.76 | GCK (0.52) | KMT2AMEN1PKMALDH1A1MAPT | |
| SCHEMBL4330589 | 0.76 | AXL (0.48) | KDRBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112876457-A | Novel 4-phenoxypyridine derivative and application thereof | 辽宁大学 | 2021-06-01 | — | — | CN | disclosed |