Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 7/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 3/20 | 0.41 |
| ▸ | UGT8 | Q16880 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.39 |
| ▸ | LIPC | P11150 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28607395 | 0.85 | HRH3 (0.48) | HRH3MCHR1LIPGLIPC | |
| SCHEMBL28607394 | 0.85 | HRH3 (0.48) | HRH3MCHR1LIPGLIPC | |
| SCHEMBL5873570 | 0.81 | MAP4K4 (0.41) | MCHR1ACACB | |
| SCHEMBL22499928 | 0.80 | NOTUM (0.53) | HRH3ACACBLIPGLIPC | |
| SCHEMBL28597269 | 0.80 | NOTUM (0.53) | HRH3ACACBLIPGLIPC | |
| Hydrochloric Acid SCHEMBL5873525 | 0.80 | MCHR1 (0.73) | MCHR1 | |
| SCHEMBL28603230 | 0.80 | LIPG (0.49) | ACACBLIPGLIPC | |
| SCHEMBL28595539 | 0.80 | LIPG (0.49) | ACACBLIPGLIPC | |
| SCHEMBL28601499 | 0.78 | SYK (0.57) | MCHR1 | |
| SCHEMBL28601501 | 0.78 | SYK (0.57) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164461-A | Heterocyclic derivatives as Nav1.7 and Nav1.8 blockers | 拉夸里亚创药株式会社 | 2021-07-23 | — | — | CN | disclosed |