Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 5/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 5/20 | 0.43 |
| ▸ | RELA | Q04206 | 5/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28601660 | 1.00 | GAA (0.48) | GAANFKB1NFKB2RELABTK | |
| SCHEMBL9906480 | 0.81 | GAA (0.50) | GAANFKB1NFKB2RELABTK | |
| SCHEMBL4703211 | 0.79 | GAA (0.48) | GAANFKB1NFKB2RELABTK | |
| SCHEMBL4699843 | 0.79 | GAA (0.48) | GAANFKB1NFKB2RELABTK | |
| SCHEMBL26317923 | 0.78 | KMT2A (0.45) | GAAKMT2AL3MBTL1 | |
| SCHEMBL8406024 | 0.76 | GAA (0.59) | GAAKMT2AL3MBTL1POLB | |
| SCHEMBL9906478 | 0.75 | GAA (0.45) | GAANFKB1NFKB2RELAF2 | |
| SCHEMBL28523674 | 0.74 | GAA (0.44) | GAANFKB1NFKB2RELAF2 | |
| SCHEMBL4760840 | 0.73 | GAA (0.45) | GAANFKB1NFKB2RELA | |
| SCHEMBL29048164 | 0.73 | SMN1; SMN2 (0.57) | GAAKMT2AL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112512589-A | Dimeric immunomodulatory compounds against CEREBLON-based mechanisms | H·李·莫菲特癌症中心研究有限公司 | 2021-03-16 | — | — | CN | disclosed |