Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | STAT6 | P42226 | 1/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5132571 | 0.86 | NPY1R (0.59) | KMT2AL3MBTL1NPY1RSCN9A | |
| SCHEMBL7416762 | 0.86 | NPY1R (0.59) | KMT2AL3MBTL1NPY1RSCN9A | |
| SCHEMBL26322639 | 0.84 | KLK7 (0.46) | KMT2AL3MBTL1NPY1RSCN9A | |
| SCHEMBL3932081 | 0.84 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1POLBKMT2AMAPT | |
| SCHEMBL6216047 | 0.84 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1POLBKMT2AMAPT | |
| SCHEMBL3932072 | 0.84 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1POLBKMT2AMAPT | |
| SCHEMBL2325330 | 0.84 | NPY1R (0.45) | SMN1; SMN2ALDH1A1POLBKMT2AL3MBTL1 | |
| SCHEMBL9636282 | 0.83 | SMN1; SMN2 (0.64) | SMN1; SMN2ALDH1A1POLBKMT2AMAPT | |
| SCHEMBL26745906 | 0.82 | KLK7 (0.46) | SMN1; SMN2ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL2847250 | 0.82 | NPY1R (0.49) | SMN1; SMN2ALDH1A1KMT2AL3MBTL1NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283990-B | Application of substituted pyrrolidone compound as tumor necrosis factor inhibitor | 沈阳药科大学 | 2023-12-15 | — | — | CN | disclosed |
| CN-116283990-A | Application of substituted pyrrolidone compound as tumor necrosis factor inhibitor | 沈阳药科大学 | 2023-06-23 | — | — | CN | disclosed |