SCHEMBL2860187

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2870967	0.85	TTK (0.47)	TTKKDM4EALDH1A1AURKAP2RY14
	SCHEMBL2868870	0.79	ITK (0.59)	KDM4EALDH1A1POLBHPGDHSD17B10
	SCHEMBL2867307	0.76	MKNK1 (0.48)	MKNK1TTKKDM4EALDH1A1AURKA
	SCHEMBL2862936	0.75	KDR (0.47)	TTKHSD17B10AURKAITKCDK2
	SCHEMBL13207534	0.75	TTK (0.47)	TTKKDM4EALDH1A1HSD17B10AURKA
	SCHEMBL2867364	0.75	LRRK2 (0.53)	ITK
	SCHEMBL5381355	0.74	ITK (0.47)	TTKKDM4EALDH1A1HPGDHSD17B10
	SCHEMBL2857635	0.74	ITK (0.46)	TTKKDM4EALDH1A1HSD17B10AURKA
	SCHEMBL2861387	0.73	ULK1 (0.59)	PSMB8ITK
	SCHEMBL17594115	0.73	MEN1 (0.67)	PSMB8ROCK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.