Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.30 |
| ▸ | GABRD | O14764 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.30 |
| ▸ | GABRE | P78334 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.30 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.30 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.30 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25671 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL4425049 | 0.80 | — | — | |
| Water SCHEMBL15879966 | 0.80 | — | — | |
| SCHEMBL16837816 | 0.80 | KDM4E (0.35) | KDM4EKMT2A | |
| SCHEMBL471835 | 0.78 | CYP2C19 (0.34) | — | |
| SCHEMBL8768141 | 0.78 | — | — | |
| Vinyl Chloride SCHEMBL2308804 | 0.76 | FFAR3 (0.31) | — | |
| Acrylic Acid SCHEMBL1652920 | 0.76 | LMNA (0.50) | KMT2A | |
| SCHEMBL648973 | 0.76 | CYP2C19 (0.38) | KMT2ATSHR | |
| SCHEMBL31170659 | 0.75 | KDM4E (0.36) | KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227103-A | Trisubstituted heteroaryl derivatives as SRC homologous-2 phosphatase inhibitors | 尼坎医疗公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-112996795-A | Fused tricyclic derivatives as SRC homologous-2 phosphatase inhibitors | 尼坎医疗公司 | 2021-06-18 | — | — | CN | disclosed |