Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28603430 | 0.75 | HTR2A (0.35) | — | |
| SCHEMBL28601867 | 0.74 | — | — | |
| SCHEMBL23645453 | 0.73 | SIGMAR1 (0.37) | — | |
| SCHEMBL29793198 | 0.70 | SIGMAR1 (0.33) | — | |
| SCHEMBL19828185 | 0.70 | SIGMAR1 (0.33) | — | |
| SCHEMBL22507670 | 0.68 | CA1 (0.32) | — | |
| SCHEMBL28919761 | 0.67 | SIGMAR1 (0.34) | — | |
| SCHEMBL30291391 | 0.66 | SIGMAR1 (0.38) | — | |
| SCHEMBL2359795 | 0.64 | HTR2C (0.41) | — | |
| SCHEMBL3400338 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113087700-B | Spirocyclic tetrahydroquinazolines | 苏州亚盛药业有限公司 | 2023-03-14 | — | — | CN | disclosed |
| CN-113087700-A | Spirocyclic tetrahydroquinazolines | 苏州亚盛药业有限公司 | 2021-07-09 | — | — | CN | disclosed |