Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K3 | P46734 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29838670 | 0.78 | CYP19A1 (0.54) | LMNAMAPTCYP1A2CYP3A4KDM4E | |
| SCHEMBL28595582 | 0.78 | CYP19A1 (0.54) | LMNAMAPTCYP1A2CYP3A4KDM4E | |
| SCHEMBL11228950 | 0.75 | MAP2K3 (0.58) | MAP2K3AAK1PIK3CBPIK3CDPIK3CG | |
| SCHEMBL28607324 | 0.74 | MAPT (0.48) | MAP2K3GSK3BPIK3CBPIK3CDPIK3CG | |
| SCHEMBL15750049 | 0.74 | ADORA2A (0.64) | MAP2K3GSK3BACHEPIK3CBPIK3CD | |
| SCHEMBL23086940 | 0.73 | MAP4K4 (0.54) | ACHEAAK1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL30873836 | 0.73 | ADK (0.42) | GSK3BPIK3CBPIK3CDPIK3CGCYP1A2 | |
| SCHEMBL22411323 | 0.73 | ADK (0.42) | GSK3BPIK3CBPIK3CDPIK3CGCYP1A2 | |
| SCHEMBL11374306 | 0.72 | PRKCD (0.56) | CYP1A2 | |
| SCHEMBL11373185 | 0.72 | PRKCH (0.47) | MAPTCYP1A2KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112368282-B | Azabenzimidazole compounds and medicaments | 日本新药株式会社 | 2023-10-13 | — | — | CN | disclosed |
| CN-114929697-A | Azabenzimidazole compounds and medicaments | 日本新药株式会社 | 2022-08-19 | — | — | CN | disclosed |
| CN-114901283-A | Therapeutic and prophylactic agent for functional digestive tract disorder and xerostomia | 日本新药株式会社 | 2022-08-12 | — | — | CN | disclosed |
| CN-112368282-A | Azabenzimidazole compounds and pharmaceuticals | 日本新药株式会社 | 2021-02-12 | — | — | CN | disclosed |