Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CCND1 | P24385 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28358032 | 0.84 | SMN1; SMN2 (0.34) | SMN1; SMN2KDM4EALDH1A1TSHRSLC22A12 | |
| SCHEMBL28470585 | 0.81 | KDM4E (0.41) | SMN1; SMN2KDM4EALDH1A1HTTNOS3 | |
| SCHEMBL9988870 | 0.81 | SLC22A12 (0.40) | SMN1; SMN2KDM4EALDH1A1TSHRSLC22A12 | |
| SCHEMBL1662137 | 0.75 | GBA1 (0.40) | KDM4EALDH1A1TSHRMAPT | |
| SCHEMBL31419110 | 0.75 | GBA1 (0.40) | KDM4EALDH1A1TSHRMAPT | |
| SCHEMBL29049963 | 0.74 | LMNA (0.46) | ALDH1A1MEN1KMT2A | |
| SCHEMBL12434098 | 0.73 | KDM4E (0.37) | SMN1; SMN2KDM4EALDH1A1NOS3NOS1 | |
| SCHEMBL28847152 | 0.72 | — | — | |
| SCHEMBL28381226 | 0.71 | NPSR1 (0.33) | ALDH1A1CDK2MAPT | |
| SCHEMBL15526300 | 0.71 | SLC22A12 (0.41) | SMN1; SMN2KDM4EALDH1A1TSHRSLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112812105-B | Aminopyridyloxy pyrazole derivative, and preparation method and application thereof | 苏州阿尔脉生物科技有限公司 | 2025-04-01 | — | — | CN | disclosed |
| CN-112812105-A | Aminopyridyloxypyrazole derivative and preparation method and application thereof | 苏州阿尔脉生物科技有限公司 | 2021-05-18 | — | — | CN | disclosed |