Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 4/20 | 0.60 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.51 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.49 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.49 |
| ▸ | RARB | P10826 | 2/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5721008 | 0.83 | ALDH1A1 (0.47) | S1PR2S1PR1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL5721010 | 0.83 | ALDH1A1 (0.47) | S1PR2S1PR1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL23512478 | 0.79 | S1PR1 (0.44) | S1PR2S1PR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL27555905 | 0.78 | KMT2A (0.48) | SMN1; SMN2THRB | |
| SCHEMBL8986801 | 0.77 | HSD17B10 (0.54) | S1PR2S1PR1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL12473375 | 0.77 | S1PR2 (0.64) | S1PR2S1PR1ALDH1A1S1PR3CYSLTR2 | |
| SCHEMBL15614012 | 0.77 | ALDH1A1 (0.53) | S1PR2S1PR1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL1138613 | 0.75 | FFAR1 (0.50) | SMN1; SMN2 | |
| SCHEMBL1138675 | 0.75 | FFAR1 (0.50) | SMN1; SMN2 | |
| SCHEMBL6965546 | 0.75 | FFAR1 (0.50) | SMN1; SMN2NPC1RAB9AKIF11THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077994-B1 | IMIDAZOLIDINE DERIVATIVES, THE PRODUCTION THEREOF, THEIR USE AND PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME | SANOFI AVENTIS DEUTSCHLAND (DE) | 2010-01-20 | — | — | EP | disclosed |
| US-6667334-B1 | Inhibitors of adhesion and migration of leukocytes and/or antagonists of adhesion receptor VLA-4 belonging to integrins group | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-12-23 | — | — | US | disclosed |
| EP-1077994-A1 | IMIDAZOLIDINE DERIVATIVES, THE PRODUCTION THEREOF, THEIR USE AND PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME | Aventis Pharma Deutschland GmbH (DE) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999060015-A1 | IMIDAZOLIDINE DERIVATIVES, THE PRODUCTION THEREOF, THEIR USE AND PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 1999-11-25 | — | — | WO | disclosed |