Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.56 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.54 |
| ▸ | RAD52 | P43351 | 1/20 | 0.51 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28583934 | 1.00 | ALDH1A1 (0.56) | ALDH1A1LMNAUSP2HSP90AA1MAPT | |
| SCHEMBL28583936 | 1.00 | ALDH1A1 (0.56) | ALDH1A1LMNAUSP2HSP90AA1MAPT | |
| SCHEMBL21093340 | 0.96 | ALDH1A1 (0.55) | ALDH1A1LMNAUSP2HSP90AA1MAPT | |
| SCHEMBL28600487 | 0.96 | ALDH1A1 (0.55) | ALDH1A1LMNAUSP2HSP90AA1MAPT | |
| SCHEMBL14429909 | 0.95 | ALDH1A1 (0.54) | ALDH1A1LMNAUSP2HSP90AA1MAPT | |
| SCHEMBL28579962 | 0.95 | ALDH1A1 (0.54) | ALDH1A1LMNAUSP2HSP90AA1MAPT | |
| SCHEMBL28589445 | 0.95 | ALDH1A1 (0.54) | ALDH1A1LMNAUSP2HSP90AA1MAPT | |
| SCHEMBL28590221 | 0.92 | ALDH1A1 (0.58) | ALDH1A1LMNAUSP2HSP90AA1MAPT | |
| SCHEMBL21093338 | 0.85 | ALDH1A1 (0.56) | ALDH1A1LMNAUSP2HSP90AA1MAPT | |
| SCHEMBL30645234 | 0.85 | ALDH1A1 (0.56) | ALDH1A1LMNAUSP2HSP90AA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106518750-B | Carbazole amino alcohol compound, preparation method thereof and application of carbazole amino alcohol compound in resisting parasitic diseases | 中国疾病预防控制中心寄生虫病预防控制所 | 2021-06-01 | — | — | CN | claimed |
| CN-106518750-B | Carbazole amino alcohol compound, preparation method thereof and application of carbazole amino alcohol compound in resisting parasitic diseases | 中国疾病预防控制中心寄生虫病预防控制所 | 2021-06-01 | — | — | CN | disclosed |