SCHEMBL28604277

SCHEMBL28604277

O=C1c2c(Br)ccc(Br)c2C(=O)N1[C@@H]1CCCc2ccccc21

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 5/20 0.47
OPRK1 P41145 5/20 0.47
OPRL1 P41146 5/20 0.47
CHRNA7 P36544 1/20 0.45
PDE7A Q13946 1/20 0.45
PDE7B Q9NP56 1/20 0.45
AHR P35869 1/20 0.43
OPRD1 P41143 2/20 0.40
IDO1 P14902 2/20 0.40
LMNA P02545 1/20 0.39
KMT2A Q03164 1/20 0.39
HPGD P15428 1/20 0.39
TSHR P16473 1/20 0.39
HTR2C P28335 1/20 0.38
CYP11B2 P19099 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28619535 1.00 OPRM1 (0.47) OPRM1OPRK1OPRL1CHRNA7PDE7A
SCHEMBL29688960 1.00 OPRM1 (0.47) OPRM1OPRK1OPRL1CHRNA7PDE7A
SCHEMBL29689071 1.00 OPRM1 (0.47) OPRM1OPRK1OPRL1CHRNA7PDE7A
SCHEMBL28604280 1.00 OPRM1 (0.47) OPRM1OPRK1OPRL1CHRNA7PDE7A
SCHEMBL1264462 0.83 OPRM1 (0.50) OPRM1OPRK1OPRL1CHRNA7PDE7A
SCHEMBL1265932 0.83 OPRM1 (0.50) OPRM1OPRK1OPRL1CHRNA7PDE7A
SCHEMBL30998388 0.83 OPRM1 (0.50) OPRM1OPRK1OPRL1CHRNA7PDE7A
SCHEMBL14602355 0.82 OPRM1 (0.49) OPRM1OPRK1OPRL1CHRNA7PDE7A
SCHEMBL4366273 0.78 DDB1 (0.44) OPRM1OPRK1OPRL1CHRNA7OPRD1
SCHEMBL4373314 0.78 DDB1 (0.44) OPRM1OPRK1OPRL1CHRNA7OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113121410-B Organic circular polarization luminescent material and preparation method and application thereof 华南师范大学 2022-05-20 CN disclosed
CN-113121410-A Organic circular polarization luminescent material and preparation method and application thereof 华南师范大学 2021-07-16 CN disclosed