E-Methyl Cinnamate

E-Methyl Cinnamate

SCHEMBL28606972

COC(=O)C=Cc1ccccc1.[Xe]

nearest known ligand 0.67

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.67
CA1 P00915 1/20 0.67
CA2 P00918 1/20 0.67
TYR P14679 1/20 0.67
CA7 P43166 1/20 0.67
CA9 Q16790 1/20 0.67
CA14 Q9ULX7 1/20 0.67
ALDH1A1 P00352 3/20 0.59
GLA P06280 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
HDAC3 O15379 2/20 0.57
HDAC4 P56524 2/20 0.57
HDAC1 Q13547 2/20 0.57
HDAC2 Q92769 2/20 0.57
HDAC8 Q9BY41 2/20 0.57
HDAC6 Q9UBN7 2/20 0.57
LMNA P02545 2/20 0.57
SMN1; SMN2 Q16637 2/20 0.57
MAPT P10636 2/20 0.57
TNKS O95271 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
E-Methyl Cinnamate SCHEMBL27554805 0.98 CA12 (0.69) CA12CA1CA2TYRCA7
E-Methyl Cinnamate SCHEMBL112062 0.98 CA12 (0.69) CA12CA1CA2TYRCA7
E-Methyl Cinnamate SCHEMBL27554806 0.98 CA12 (0.69) CA12CA1CA2TYRCA7
E-Methyl Cinnamate SCHEMBL1862419 0.98 CA12 (0.69) CA12CA1CA2TYRCA7
E-Methyl Cinnamate SCHEMBL101530 0.98 CA12 (0.69) CA12CA1CA2TYRCA7
E-Methyl Cinnamate SCHEMBL901224 0.98 CA12 (0.69) CA12CA1CA2TYRCA7
E-Methyl Cinnamate SCHEMBL2425288 0.98 CA12 (0.69) CA12CA1CA2TYRCA7
E-Methyl Cinnamate SCHEMBL28577208 0.96 CA12 (0.67) CA12CA1CA2TYRCA7
E-Methyl Cinnamate SCHEMBL6327040 0.96 CA12 (0.67) CA12CA1CA2TYRCA7
E-Methyl Cinnamate SCHEMBL11725144 0.96 CA12 (0.67) CA12CA1CA2TYRCA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113149942-A Rockmilanol phenolic hydroxyl derivative, preparation method and application thereof 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) 2021-07-23 CN disclosed