E-Methyl Cinnamate

E-Methyl Cinnamate

SCHEMBL901224

COC(=O)/C=C/c1ccccc1.COC(=O)/C=C/c1ccccc1

nearest known ligand 0.69

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.69
CA1 P00915 1/20 0.69
CA2 P00918 1/20 0.69
TYR P14679 1/20 0.69
CA7 P43166 1/20 0.69
CA9 Q16790 1/20 0.69
CA14 Q9ULX7 1/20 0.69
GLA P06280 1/20 0.61
TDP1 Q9NUW8 1/20 0.61
ALDH1A1 P00352 3/20 0.61
HDAC3 O15379 2/20 0.59
HDAC4 P56524 2/20 0.59
HDAC1 Q13547 2/20 0.59
HDAC2 Q92769 2/20 0.59
HDAC8 Q9BY41 2/20 0.59
HDAC6 Q9UBN7 2/20 0.59
LMNA P02545 2/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
MAPT P10636 2/20 0.59
TNKS O95271 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
E-Methyl Cinnamate SCHEMBL112062 1.00 CA12 (0.69) CA12CA1CA2TYRCA7
E-Methyl Cinnamate SCHEMBL2425288 1.00 CA12 (0.69) CA12CA1CA2TYRCA7
E-Methyl Cinnamate SCHEMBL27554805 1.00 CA12 (0.69) CA12CA1CA2TYRCA7
E-Methyl Cinnamate SCHEMBL27554806 1.00 CA12 (0.69) CA12CA1CA2TYRCA7
E-Methyl Cinnamate SCHEMBL1862419 1.00 CA12 (0.69) CA12CA1CA2TYRCA7
E-Methyl Cinnamate SCHEMBL101530 1.00 CA12 (0.69) CA12CA1CA2TYRCA7
E-Methyl Cinnamate SCHEMBL28606972 0.98 CA12 (0.67) CA12CA1CA2TYRCA7
E-Methyl Cinnamate SCHEMBL28577208 0.98 CA12 (0.67) CA12CA1CA2TYRCA7
E-Methyl Cinnamate SCHEMBL6327040 0.98 CA12 (0.67) CA12CA1CA2TYRCA7
E-Methyl Cinnamate SCHEMBL11725144 0.98 CA12 (0.67) CA12CA1CA2TYRCA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108210682-A A kind of promoting blood circulation medicine puree and preparation method for treating Osteoarthritis 黄建民 2018-06-29 CN disclosed
EP-2621462-A1 ORAL CARE COMPOSITIONS WITH IMPROVED FLAVOR The Procter and Gamble Company (US) 2013-08-07 EP disclosed
WO-2012044728-A1 ORAL CARE COMPOSITIONS WITH IMPROVED FLAVOR THE PROCTER & GAMBLE COMPANY (US) 2012-04-05 WO disclosed