Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 4/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | ABL2 | P42684 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13861581 | 0.86 | SRC (0.48) | HCAR1SRCEGFRFPR2HPGDS | |
| SCHEMBL13861580 | 0.86 | SRC (0.48) | HCAR1SRCEGFRFPR2HPGDS | |
| SCHEMBL28599393 | 0.84 | MAPT (0.35) | MAPTHTR6POLB | |
| SCHEMBL28599391 | 0.84 | MAPT (0.35) | MAPTHTR6POLB | |
| SCHEMBL30973451 | 0.83 | HCAR1 (0.40) | HCAR1SRCEGFRFPR2USP30 | |
| SCHEMBL17144495 | 0.82 | HCAR1 (0.45) | HCAR1SRCEGFRFPR2HPGDS | |
| SCHEMBL17143824 | 0.82 | HCAR1 (0.45) | HCAR1SRCEGFRFPR2HPGDS | |
| SCHEMBL17143823 | 0.82 | HCAR1 (0.45) | HCAR1SRCEGFRFPR2HPGDS | |
| SCHEMBL30994032 | 0.80 | SRC (0.42) | HCAR1SRCEGFRFPR2USP30 | |
| SCHEMBL9950465 | 0.80 | SRC (0.54) | SRCEGFRUSP30ABL1ABL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113214265-B | Pyrimidine five-membered ring compound | 江苏先声药业有限公司 | 2023-07-07 | — | — | CN | disclosed |
| CN-113214265-A | Pyrimido five-membered ring compounds | 江苏先声药业有限公司 | 2021-08-06 | — | — | CN | disclosed |