Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 4/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28614670 | 0.87 | CHRNB4 (0.44) | CHRNB4CHRNA3MEN1KMT2APRMT5 | |
| SCHEMBL5937030 | 0.87 | CHRNB4 (0.51) | CHRNB4CHRNA3MEN1KMT2APRMT5 | |
| SCHEMBL3583311 | 0.84 | CHRNB4 (0.48) | CHRNB4CHRNA3MEN1KMT2APRMT5 | |
| SCHEMBL1011265 | 0.82 | CHRNB4 (0.51) | CHRNB4CHRNA3MEN1KMT2ANPC1 | |
| SCHEMBL6925938 | 0.82 | CHRNB4 (0.51) | CHRNB4CHRNA3MEN1KMT2ANPC1 | |
| SCHEMBL1011267 | 0.82 | CHRNB4 (0.51) | CHRNB4CHRNA3MEN1KMT2ANPC1 | |
| SCHEMBL16715355 | 0.82 | CHRNB4 (0.54) | CHRNB4CHRNA3MEN1KMT2ANPC1 | |
| SCHEMBL5846431 | 0.82 | CHRNB4 (0.51) | CHRNB4CHRNA3MEN1KMT2ANPC1 | |
| SCHEMBL5937089 | 0.82 | CHRNB4 (0.51) | CHRNB4CHRNA3MEN1KMT2APRMT5 | |
| SCHEMBL5937120 | 0.81 | MEN1 (0.46) | CHRNB4CHRNA3MEN1KMT2APRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109422737-B | Imidazolone androgen receptor antagonist, preparation method and application thereof | 上海时莱生物技术有限公司 | 2021-07-30 | — | — | CN | disclosed |