Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.60 |
| ▸ | HPGDS | O60760 | 3/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27878871 | 0.87 | POLB (0.50) | EPHX1ALPIPKMPTGS1XIAP | |
| SCHEMBL28770357 | 0.87 | EPHX1 (0.46) | EPHX1ALPIPKMPTGS1XIAP | |
| SCHEMBL5176590 | 0.83 | TP53 (0.44) | EPHX1ALOX5ALDH1A1MEN1KMT2A | |
| SCHEMBL6712871 | 0.80 | ESR1 (0.47) | HPGDALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL10210730 | 0.78 | ALOX5 (0.50) | ALOX5HPGDCES2CES1KEAP1 | |
| SCHEMBL6464486 | 0.78 | ALOX5 (0.50) | ALOX5HPGDCES2CES1KEAP1 | |
| SCHEMBL27986401 | 0.77 | EPHX1 (0.55) | EPHX1HPGDSALPIPKMPTGS1 | |
| SCHEMBL7831698 | 0.77 | HSD17B2 (0.42) | EPHX1PKMALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL11903248 | 0.76 | ALOX5 (0.46) | EPHX1PKMALOX5HPGDALDH1A1 | |
| SCHEMBL3906596 | 0.75 | SLC5A2 (0.52) | EPHX1CES2CES1KEAP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113214104-B | Method for synthesizing aromatic acetamide | 浙江工业大学 | 2022-05-24 | — | — | CN | disclosed |
| CN-113214104-A | Method for synthesizing aromatic acetamide | 浙江工业大学 | 2021-08-06 | — | — | CN | disclosed |