Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29786163 | 1.00 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNARECQLHTTPOLB | |
| SCHEMBL9335519 | 0.82 | POLB (0.46) | SMN1; SMN2LMNARECQLHTTPOLB | |
| SCHEMBL9335456 | 0.81 | MAPT (0.46) | SMN1; SMN2LMNARECQLHTTPOLB | |
| SCHEMBL19982873 | 0.81 | SMN1; SMN2 (0.54) | SMN1; SMN2LMNARECQLHTTPOLB | |
| SCHEMBL7738315 | 0.79 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNARECQLHTTPOLB | |
| SCHEMBL760729 | 0.77 | SMN1; SMN2 (0.57) | SMN1; SMN2LMNARECQLHTTPOLB | |
| SCHEMBL6990517 | 0.75 | SMN1; SMN2 (0.55) | SMN1; SMN2LMNARECQLHTTPOLB | |
| SCHEMBL2729927 | 0.74 | SMN1; SMN2 (0.61) | SMN1; SMN2LMNARECQLHTTPOLB | |
| SCHEMBL16488211 | 0.72 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNARECQLHTTPOLB | |
| SCHEMBL2676424 | 0.72 | KLK5 (0.57) | SMN1; SMN2LMNARECQLHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894345-A | Method for photocatalytic synthesis of chiral aza-arene functionalized cyclobutane compound | 河南工业大学 | 2023-04-04 | — | — | CN | disclosed |
| CN-113248422-B | Chiral alpha-aza-arene quaternary carbon center compound, and preparation method and application thereof | 河南工业大学 | 2022-07-12 | — | — | CN | disclosed |
| CN-113248422-A | Chiral alpha-azaarene quaternary carbon center compound, and preparation method and application thereof | 河南工业大学 | 2021-08-13 | — | — | CN | disclosed |