Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7738315 | 0.84 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1LMNAHTTRECQL | |
| SCHEMBL2729927 | 0.81 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1LMNAHTTRECQL | |
| SCHEMBL28607407 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1LMNAHTTRECQL | |
| SCHEMBL29786163 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1LMNAHTTRECQL | |
| SCHEMBL6990517 | 0.79 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1LMNAHTTRECQL | |
| SCHEMBL760729 | 0.78 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1LMNAHTTRECQL | |
| SCHEMBL2596342 | 0.77 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1LMNAHTTRECQL | |
| SCHEMBL17470433 | 0.77 | MAPK1 (0.57) | ALDH1A1LMNAHTTRECQLKDM4E | |
| SCHEMBL6028575 | 0.76 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1LMNAHTTRECQL | |
| SCHEMBL16488211 | 0.76 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1LMNAHTTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154766-A1 | KRAS MODULATORS AND USES THEREOF | QUANTA THERAPEUTICS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |
| EP-2881394-B1 | CONDENSED RING HETEROCYCLIC COMPOUND | KYOWA HAKKO KIRIN CO LTD (JP) | 2018-03-21 | — | — | EP | disclosed |