Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28607611 | 1.00 | KDM4E (0.53) | KDM4EMAPTALDH1A1LMNATSHR | |
| SCHEMBL21597779 | 0.91 | KMT2A (0.59) | KDM4EMAPTALDH1A1LMNATSHR | |
| SCHEMBL28610753 | 0.89 | MAPT (0.55) | KDM4EMAPTALDH1A1LMNATSHR | |
| SCHEMBL28610613 | 0.89 | MAPT (0.55) | KDM4EMAPTALDH1A1LMNATSHR | |
| SCHEMBL28611808 | 0.87 | KMT2A (0.51) | KDM4EMAPTALDH1A1LMNATSHR | |
| SCHEMBL28610544 | 0.86 | KDM4E (0.57) | KDM4EMAPTALDH1A1LMNATSHR | |
| SCHEMBL28610570 | 0.85 | KDM4E (0.52) | KDM4EMAPTALDH1A1LMNATSHR | |
| SCHEMBL28612056 | 0.82 | KDM4E (0.48) | KDM4EMAPTALDH1A1LMNATSHR | |
| SCHEMBL28612057 | 0.82 | KDM4E (0.48) | KDM4EMAPTALDH1A1LMNATSHR | |
| SCHEMBL30148439 | 0.81 | MAPT (0.52) | KDM4EMAPTALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112566910-A | Thiophene derivatives for the treatment of IgE induced diseases | UCB生物制药有限责任公司 | 2021-03-26 | — | — | CN | disclosed |