Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | PI4KA | P42356 | 2/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.42 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.42 |
| ▸ | AHCY | P23526 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28607691 | 0.84 | ADORA2A (0.51) | ADORA2AADORA2BADORA1PI4KAPI4K2B | |
| SCHEMBL28045212 | 0.80 | CYP3A4 (0.66) | CYP3A4 | |
| SCHEMBL19370540 | 0.80 | CYP3A4 (0.66) | CYP3A4 | |
| SCHEMBL14849943 | 0.80 | CYP3A4 (0.66) | CYP3A4 | |
| SCHEMBL6402722 | 0.80 | CYP3A4 (0.61) | ADORA2AADORA2BADORA1PI4KAPI4K2B | |
| SCHEMBL28462922 | 0.78 | ADORA2A (0.48) | ADORA2AADORA2BADORA1PI4KAPI4K2B | |
| SCHEMBL20324318 | 0.77 | CYP3A4 (0.48) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL29641197 | 0.76 | PI4KA (0.46) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL21518150 | 0.76 | PI4KA (0.46) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL21518153 | 0.76 | PI4KA (0.46) | ADORA2AADORA1PI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109265480-B | Preparation method of high-purity tenofovir alafenamide impurity TAF-Y | 扬子江药业集团有限公司 | 2021-08-13 | — | — | CN | claimed |
| CN-109265480-B | Preparation method of high-purity tenofovir alafenamide impurity TAF-Y | 扬子江药业集团有限公司 | 2021-08-13 | — | — | CN | disclosed |