Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 6/20 | 0.44 |
| ▸ | JAK2 | O60674 | 7/20 | 0.44 |
| ▸ | JAK1 | P23458 | 7/20 | 0.44 |
| ▸ | BTK | Q06187 | 5/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28618092 | 0.94 | JAK2 (0.47) | PARP1JAK2JAK1 | |
| SCHEMBL28607007 | 0.88 | PARP1 (0.48) | PARP1JAK2JAK1 | |
| SCHEMBL28624126 | 0.86 | PARP1 (0.55) | PARP1JAK2JAK1BTK | |
| SCHEMBL2267080 | 0.85 | BTK (0.45) | PARP1BTK | |
| SCHEMBL2270749 | 0.84 | CCNT1 (0.41) | PARP1JAK2JAK1 | |
| SCHEMBL28779527 | 0.83 | PARP1 (0.41) | PARP1BTK | |
| SCHEMBL2264558 | 0.82 | PARP1 (0.54) | PARP1BTK | |
| SCHEMBL15472790 | 0.80 | JAK2 (0.45) | PARP1JAK2JAK1BTKCHEK2 | |
| SCHEMBL2262723 | 0.80 | PARP1 (0.42) | PARP1BTK | |
| SCHEMBL30158153 | 0.80 | KDM2B (0.45) | PARP1BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113288892-B | Use of poly ADP-ribose polymerase inhibitors against coronaviruses | 甫康（上海）健康科技有限责任公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-113288892-A | Application of poly ADP ribose polymerase inhibitor in resisting coronavirus | 甫康（上海）健康科技有限责任公司 | 2021-08-24 | — | — | CN | disclosed |