Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 7/20 | 0.47 |
| ▸ | JAK1 | P23458 | 7/20 | 0.47 |
| ▸ | PARP1 | P09874 | 11/20 | 0.47 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.40 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.40 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28607992 | 0.94 | PARP1 (0.44) | JAK2JAK1PARP1 | |
| SCHEMBL28607007 | 0.94 | PARP1 (0.48) | JAK2JAK1PARP1IRAK4PARP2 | |
| SCHEMBL2270749 | 0.89 | CCNT1 (0.41) | JAK2JAK1PARP1 | |
| SCHEMBL2268203 | 0.84 | PARP1 (0.45) | PARP1PARP2FGFR1FGFR2FGFR4 | |
| SCHEMBL27908945 | 0.83 | EGFR (0.38) | JAK2JAK1 | |
| SCHEMBL27908947 | 0.83 | GPR119 (0.41) | JAK2JAK1 | |
| SCHEMBL30158077 | 0.81 | PARP1 (0.52) | PARP1IRAK4PARP2 | |
| SCHEMBL27759081 | 0.81 | PARP1 (0.42) | PARP1IRAK4PARP2 | |
| SCHEMBL2264886 | 0.80 | PARP1 (0.42) | PARP1IRAK4PARP2FGFR1FGFR2 | |
| SCHEMBL2267407 | 0.80 | PARP1 (0.46) | PARP1IRAK4PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113288892-B | Use of poly ADP-ribose polymerase inhibitors against coronaviruses | 甫康（上海）健康科技有限责任公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-113288892-A | Application of poly ADP ribose polymerase inhibitor in resisting coronavirus | 甫康（上海）健康科技有限责任公司 | 2021-08-24 | — | — | CN | disclosed |