Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28602335 | 0.90 | HSP90AA1 (0.57) | HSP90AA1NPSR1GAAHSD17B10CYP3A4 | |
| SCHEMBL28608936 | 0.90 | HSP90AA1 (0.57) | HSP90AA1NPSR1GAAHSD17B10CYP3A4 | |
| SCHEMBL11544305 | 0.90 | HSP90AA1 (0.57) | HSP90AA1NPSR1GAAHSD17B10CYP3A4 | |
| SCHEMBL9458140 | 0.90 | HSP90AA1 (0.47) | HSP90AA1NPSR1GAAHSD17B10CYP3A4 | |
| SCHEMBL9458028 | 0.88 | HSP90AA1 (0.63) | HSP90AA1NPSR1GAAHSD17B10CYP3A4 | |
| SCHEMBL28602340 | 0.88 | HSP90AA1 (0.56) | HSP90AA1NPSR1GAAHSD17B10CYP3A4 | |
| SCHEMBL28612952 | 0.88 | HSP90AA1 (0.56) | HSP90AA1NPSR1GAAHSD17B10CYP3A4 | |
| SCHEMBL11547531 | 0.88 | HSP90AA1 (0.56) | HSP90AA1NPSR1GAAHSD17B10CYP3A4 | |
| SCHEMBL1280255 | 0.86 | HSP90AA1 (0.45) | HSP90AA1NPSR1GAAHSD17B10CYP3A4 | |
| SCHEMBL1279944 | 0.86 | HSP90AA1 (0.44) | HSP90AA1NPSR1GAAHSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5266585-A | Controlling phytopathogenic microorganisms, fungicides, antimycotics, anticonvulsives and/or anxiolytic agents | CIBA-GEIGY CORPORATION (US) | 1993-11-30 | — | — | US | claimed |
| EP-0065485-B1 | ARYLPHENYL ETHER DERIVATIVES AS MICROBICIDES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION | CIBA-GEIGY AG (CH) | 1990-04-18 | — | — | EP | claimed |
| EP-0065485-A2 | Arylphenyl ether derivatives as microbicides, process for their preparation and their application | CIBA-GEIGY AG (CH) | 1982-11-24 | — | — | EP | claimed |
| US-5266585-A | Controlling phytopathogenic microorganisms, fungicides, antimycotics, anticonvulsives and/or anxiolytic agents | CIBA-GEIGY CORPORATION (US) | 1993-11-30 | — | — | US | disclosed |
| EP-0065485-B1 | ARYLPHENYL ETHER DERIVATIVES AS MICROBICIDES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION | CIBA-GEIGY AG (CH) | 1990-04-18 | — | — | EP | disclosed |
| EP-0065485-A2 | Arylphenyl ether derivatives as microbicides, process for their preparation and their application | CIBA-GEIGY AG (CH) | 1982-11-24 | — | — | EP | disclosed |