SCHEMBL28609059

SCHEMBL28609059

COc1nc(C)nc(CN(Cc2ccccc2C(=O)O)C(=O)OS(N)(=O)=O)n1

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
CYP2C9 P11712 1/20 0.33
HIF1A Q16665 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
TAS2R14 Q9NYV8 3/20 0.31
LTB4R2 Q9NPC1 1/20 0.31
CETP P11597 1/20 0.30
USP2 O75604 1/20 0.30
TP53 P04637 1/20 0.30
NPC1 O15118 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28597888 0.84 ALDH1A1 (0.32) ALDH1A1LMNATDP1USP2TP53
SCHEMBL5484371 0.73 F2 (0.40) CA9ALDH1A1TAS2R14TSHR
SCHEMBL28543743 0.68 CYP2C9 (0.36) ALDH1A1LMNACYP2C9HIF1ANPC1
SCHEMBL28542885 0.67 CYP2C9 (0.35) ALDH1A1LMNACYP2C9HIF1ANPC1
SCHEMBL28505905 0.66 ATM (0.35) ALDH1A1LMNACYP2C9HIF1ANPC1
SCHEMBL1827311 0.65 CA12 (0.42) CA1CA2CA9ALDH1A1NPC1
SCHEMBL10970826 0.65 TP53 (0.38) CA2CA9ALDH1A1TP53NPC1
SCHEMBL31126879 0.62 ABCC1 (0.47) ALDH1A1LMNACYP2C9TSHR
SCHEMBL31126861 0.61 TP53 (0.47) ALDH1A1LMNALTB4R2TP53TSHR
SCHEMBL7693190 0.60 CA1 (0.43) CA1CA2CA9NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109497083-B Medicament for removing flying cotton and fly of plants and application thereof 北京市园林科学研究院 2021-07-30 CN disclosed