Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | CDC7 | O00311 | 5/20 | 0.31 |
| ▸ | CDK2 | P24941 | 5/20 | 0.31 |
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CASP6 | P55212 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31413331 | 0.76 | PRKCI (0.42) | PRKCIMAPTROCK1BRPF1CDC7 | |
| SCHEMBL21925193 | 0.76 | PRKCI (0.42) | PRKCIMAPTROCK1BRPF1CDC7 | |
| SCHEMBL21925197 | 0.68 | MAPT (0.54) | MAPTROCK1HTR6LMNA | |
| SCHEMBL31413335 | 0.68 | MAPT (0.54) | MAPTROCK1HTR6LMNA | |
| SCHEMBL15712770 | 0.67 | SMN1; SMN2 (0.55) | PRKCIMAPTHTR6CDC7CDK2 | |
| SCHEMBL4949297 | 0.67 | PRKCI (0.45) | PRKCIMAPTBRPF1HTR6KDM4E | |
| SCHEMBL29507010 | 0.65 | PRKCI (0.70) | PRKCIMAPTBRPF1HTR6KDM4E | |
| SCHEMBL398452 | 0.65 | PRKCI (0.70) | PRKCIMAPTBRPF1HTR6KDM4E | |
| SCHEMBL5718697 | 0.65 | PRKCI (0.70) | PRKCIMAPTBRPF1HTR6KDM4E | |
| SCHEMBL4949216 | 0.65 | PRKCI (0.44) | PRKCIMAPTROCK1BRPF1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113286581-A | Intraocular or oral administration of pharmaceutical compositions for the treatment of retinal diseases | 扶桑药品工业株式会社 | 2021-08-20 | — | — | CN | claimed |
| CN-113271932-A | Pharmaceutical composition for treating cerebrovascular diseases and dementia | 扶桑药品工业株式会社 | 2021-08-17 | — | — | CN | claimed |
| CN-113286581-A | Intraocular or oral administration of pharmaceutical compositions for the treatment of retinal diseases | 扶桑药品工业株式会社 | 2021-08-20 | — | — | CN | disclosed |
| CN-113271932-A | Pharmaceutical composition for treating cerebrovascular diseases and dementia | 扶桑药品工业株式会社 | 2021-08-17 | — | — | CN | disclosed |