Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.70 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.53 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CASP1 | P29466 | 2/20 | 0.37 |
| ▸ | CASP7 | P55210 | 2/20 | 0.37 |
| ▸ | HBB | P68871 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL398452 | 1.00 | PRKCI (0.70) | PRKCICYP2A6PIK3CBL3MBTL1BRPF1 | |
| SCHEMBL29507010 | 1.00 | PRKCI (0.70) | PRKCICYP2A6PIK3CBL3MBTL1BRPF1 | |
| Hydrochloric Acid SCHEMBL397061 | 0.98 | PRKCI (0.68) | PRKCICYP2A6PIK3CBL3MBTL1BRPF1 | |
| SCHEMBL31039616 | 0.86 | PRKCI (0.53) | PRKCICYP2A6PIK3CBL3MBTL1BRPF1 | |
| SCHEMBL30006940 | 0.83 | PRKCI (1.00) | PRKCICYP2A6PIK3CBBRPF1EGFR | |
| SCHEMBL721707 | 0.83 | PRKCI (1.00) | PRKCICYP2A6PIK3CBBRPF1EGFR | |
| SCHEMBL5133705 | 0.82 | PRKCI (0.50) | PRKCICYP2A6MAPTALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL7350283 | 0.81 | PRKCI (0.96) | PRKCICYP2A6PIK3CBBRPF1EGFR | |
| SCHEMBL26697735 | 0.78 | PRKCI (0.49) | PRKCICYP2A6PIK3CBL3MBTL1BRPF1 | |
| SCHEMBL30775573 | 0.78 | PRKCI (0.49) | PRKCICYP2A6PIK3CBL3MBTL1BRPF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732884-A1 | SULPHONAMIDE DERIVATIVES | Biotie Therapies Corp. (FI) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005090298-A1 | SULPHONAMIDE DERIVATIVES | BIOTIE THERAPIES CORPORATION (FI) | 2005-09-29 | — | — | WO | disclosed |