SCHEMBL2860957

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12317930	0.86	IDO1 (0.63)	AURKAIDO1TTKKDM4EALDH1A1
	SCHEMBL18977088	0.82	TTK (0.75)	AURKAIDO1TTKKDM4EALDH1A1
	SCHEMBL5767752	0.81	KDM4E (0.51)	AURKAIDO1TTKKDM4EALDH1A1
	SCHEMBL14516332	0.81	AURKA (0.59)	AURKATTKMAP2K4TDO2ITK
	SCHEMBL2860721	0.81	AXL (0.61)	AURKATTKMAP2K4MAPK1MAPKAPK3
	SCHEMBL4144451	0.81	MAP2K4 (0.53)	IDO1MAP2K4TDO2LRRK2MAP2K7
	SCHEMBL4153296	0.81	CLK2 (0.52)	IDO1MAP2K4LRRK2MAP2K7
	SCHEMBL19597646	0.81	TTK (0.72)	AURKAIDO1TTKKDM4EALDH1A1
	SCHEMBL5377572	0.80	ALDH1A1 (0.71)	AURKAIDO1TTKKDM4EALDH1A1
	SCHEMBL694710	0.80	MAP2K4 (0.48)	AURKAIDO1TTKKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.