Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 9/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16922972 | 0.98 | PDK2 (0.44) | PDK2MEN1KMT2ALMNAMAPT | |
| SCHEMBL1645301 | 0.89 | SMN1; SMN2 (0.43) | PDK2MEN1KMT2ALMNAMAPT | |
| SCHEMBL16922977 | 0.89 | MEN1 (0.47) | PDK2MEN1KMT2ALMNAMAPT | |
| SCHEMBL29469448 | 0.89 | PDK2 (0.51) | PDK2MEN1KMT2ALMNAMAPT | |
| SCHEMBL802764 | 0.89 | PDK2 (0.51) | PDK2MEN1KMT2ALMNAMAPT | |
| SCHEMBL16922981 | 0.88 | MAPK1 (0.45) | PDK2MEN1KMT2ALMNAMAPT | |
| SCHEMBL28500082 | 0.87 | MEN1 (0.50) | PDK2MEN1KMT2ALMNAMAPT | |
| SCHEMBL18257054 | 0.87 | ESR1 (0.39) | PDK2MEN1KMT2ALMNAMAPT | |
| SCHEMBL17016470 | 0.87 | PDK2 (0.43) | PDK2MEN1KMT2ALMNAMAPT | |
| SCHEMBL30817484 | 0.87 | PDK2 (0.43) | PDK2MEN1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113149809-A | 9- ([1, 1' -biphenyl ] -3-yl) -9-phenyl-2-bromofluorene and synthesis method thereof | 河南省科学院化学研究所有限公司 | 2021-07-23 | — | — | CN | claimed |
| CN-113149809-A | 9- ([1, 1' -biphenyl ] -3-yl) -9-phenyl-2-bromofluorene and synthesis method thereof | 河南省科学院化学研究所有限公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-113149809-A | 9- ([1, 1' -biphenyl ] -3-yl) -9-phenyl-2-bromofluorene and synthesis method thereof | 河南省科学院化学研究所有限公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-113149809-A | 9- ([1, 1' -biphenyl ] -3-yl) -9-phenyl-2-bromofluorene and synthesis method thereof | 河南省科学院化学研究所有限公司 | 2021-07-23 | — | — | CN | disclosed |