SCHEMBL1645301

SCHEMBL1645301

Brc1cccc(-c2cccc(C3(c4ccccc4)c4ccccc4-c4ccccc43)c2)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.43
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
MAPT P10636 2/20 0.43
KDM4E B2RXH2 1/20 0.43
LMNA P02545 1/20 0.43
OPRK1 P41145 1/20 0.43
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
GABRG2 P18507 2/20 0.40
GABRB3 P28472 2/20 0.40
GABRA5 P31644 2/20 0.40
GABRA3 P34903 2/20 0.40
GABRA1 P14867 1/20 0.40
NPC1 O15118 2/20 0.39
TSHR P16473 2/20 0.39
RAB9A P51151 2/20 0.39
TP53 P04637 1/20 0.39
IDO1 P14902 1/20 0.39
TDP2 O95551 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18257054 0.91 ESR1 (0.39) SMN1; SMN2MEN1KMT2AMAPTKDM4E
SCHEMBL30817484 0.91 PDK2 (0.43) SMN1; SMN2MEN1KMT2AMAPTKDM4E
SCHEMBL30817485 0.91 PDK2 (0.43) SMN1; SMN2MEN1KMT2AMAPTKDM4E
SCHEMBL23264469 0.91 SMN1; SMN2 (0.45) SMN1; SMN2MEN1KMT2AMAPTKDM4E
SCHEMBL17016470 0.91 PDK2 (0.43) SMN1; SMN2MEN1KMT2AMAPTKDM4E
SCHEMBL283740 0.90 MEN1 (0.48) SMN1; SMN2MEN1KMT2AMAPTKDM4E
SCHEMBL30726502 0.90 MEN1 (0.48) SMN1; SMN2MEN1KMT2AMAPTKDM4E
SCHEMBL29740923 0.90 MEN1 (0.48) SMN1; SMN2MEN1KMT2AMAPTKDM4E
SCHEMBL28610052 0.89 PDK2 (0.43) SMN1; SMN2MEN1KMT2AMAPTKDM4E
SCHEMBL17816640 0.88 MEN1 (0.47) SMN1; SMN2MEN1KMT2AMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022004994-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME 덕산네오룩스 주식회사 2022-01-06 WO disclosed
US-20170104157-A1 FLUORENE DERIVATIVE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-04-13 US disclosed
US-20170104157-A1 FLUORENE DERIVATIVE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-04-13 US disclosed
US-20170104157-A1 FLUORENE DERIVATIVE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-04-13 US disclosed
US-9553273-B2 Fluorene derivative, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-01-24 US disclosed
US-9553273-B2 Fluorene derivative, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-01-24 US disclosed
US-9553273-B2 Fluorene derivative, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-01-24 US disclosed
CN-104946243-A Fluorene derivative, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCOTR ENERGY LAB CO LTD 2015-09-30 CN disclosed
CN-102040528-B Fluorene derivative, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO.,LTD. (JP) 2015-08-05 CN disclosed
CN-103102277-B Fluorene derivative, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-10-22 CN disclosed
US-8642190-B2 Fluorene derivative, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-02-04 US disclosed
US-8642190-B2 Fluorene derivative, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-02-04 US disclosed
EP-2314565-B1 Fluorene Derivative, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LAB (JP) 2013-07-24 EP disclosed
EP-2314565-B1 Fluorene Derivative, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LAB (JP) 2013-07-24 EP disclosed
CN-102040528-A Fluorene derivative, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LAB 2011-05-04 CN disclosed
US-20110095678-A1 FLUORENE DERIVATIVE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-04-28 US disclosed
US-20110095678-A1 FLUORENE DERIVATIVE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-04-28 US disclosed
US-20110095678-A1 FLUORENE DERIVATIVE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-04-28 US disclosed
EP-2314565-A1 Fluorene Derivative, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-04-27 EP disclosed
EP-2314565-A1 Fluorene Derivative, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-04-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170104157-A1 FLUORENE DERIVATIVE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE NR2E3, AFF1, LEF1 SMN1; SMN2 2584/4885MEN1 953/4885KMT2A 869/4885
US-20110095678-A1 FLUORENE DERIVATIVE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE NR2E3, AFF1, LEF1 SMN1; SMN2 2584/4885MEN1 953/4885KMT2A 869/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.