SCHEMBL28610231

SCHEMBL28610231

CCCCCN(CCCCC)C(=O)NCC(N)=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.41
KDM4E B2RXH2 2/20 0.40
SOAT1 P35610 2/20 0.40
CA12 O43570 5/20 0.39
CA1 P00915 5/20 0.39
CA9 Q16790 5/20 0.39
CA2 P00918 3/20 0.39
MEN1 O00255 1/20 0.39
FAAH O00519 1/20 0.39
TP53 P04637 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C19 P33261 1/20 0.39
KMT2A Q03164 1/20 0.39
MGLL Q99685 1/20 0.38
MMP1 P03956 1/20 0.36
MMP2 P08253 1/20 0.36
MMP3 P08254 1/20 0.36
MMP8 P22894 1/20 0.36
EPHX2 P34913 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19033745 0.79 CA12 (0.43) CNR1KDM4ESOAT1CA12CA1
SCHEMBL75710 0.79 FAAH (0.50) CA12CA1CA9CA2FAAH
SCHEMBL9403702 0.79 FAAH (0.50) CA12CA1CA9CA2FAAH
SCHEMBL18686285 0.79 EPHX1 (0.54) CA12CA1CA9FAAHEPHX2
SCHEMBL25277332 0.77 EPHX1 (0.57) FAAHMGLLEPHX2EPHX1DNM1
SCHEMBL25228713 0.77 EPHX1 (0.57) FAAHMGLLEPHX2EPHX1DNM1
SCHEMBL25220735 0.77 EPHX1 (0.57) FAAHMGLLEPHX2EPHX1DNM1
SCHEMBL25278342 0.77 EPHX1 (0.57) FAAHMGLLEPHX2EPHX1DNM1
SCHEMBL25273622 0.77 EPHX1 (0.57) FAAHMGLLEPHX2EPHX1DNM1
SCHEMBL25272238 0.77 EPHX1 (0.57) FAAHMGLLEPHX2EPHX1DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110041285-B Preparation method of 2, 4, 5-trisubstituted oxazole compound 大连理工大学 2021-08-20 CN claimed
CN-110041285-B Preparation method of 2, 4, 5-trisubstituted oxazole compound 大连理工大学 2021-08-20 CN disclosed