Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | BDKRB1 | P46663 | 3/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16709787 | 0.84 | MRGPRX4 (0.51) | MRGPRX4MAOBMAPTMEN1NPC1 | |
| SCHEMBL9937243 | 0.78 | MRGPRX4 (0.54) | MRGPRX4MAOBMAPTMEN1NPC1 | |
| SCHEMBL18423850 | 0.76 | MRGPRX4 (0.47) | MRGPRX4MAOBMAPTMEN1NPC1 | |
| SCHEMBL16709810 | 0.76 | CA1 (0.52) | MEN1NPC1RAB9AKMT2ALOXL2 | |
| SCHEMBL16709821 | 0.74 | MEN1 (0.45) | MRGPRX4MAOBMAPTMEN1KMT2A | |
| SCHEMBL18464053 | 0.74 | MEN1 (0.55) | MRGPRX4MAPTMEN1NPC1RAB9A | |
| SCHEMBL16709786 | 0.73 | L3MBTL1 (0.50) | MAPTMEN1NPC1RAB9AKMT2A | |
| SCHEMBL16709757 | 0.73 | MEN1 (0.50) | MRGPRX4MAPTMEN1NPC1RAB9A | |
| SCHEMBL16702001 | 0.72 | MRGPRX4 (0.47) | MRGPRX4MAPTMEN1NPC1RAB9A | |
| SCHEMBL18423852 | 0.72 | MRGPRX4 (0.47) | MRGPRX4MAOBMAPTMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026056-B | 1,3, 4-oxadiazole amide derivative compounds as histone deacetylase 6 inhibitors and pharmaceutical compositions thereof | 株式会社钟根堂 | 2021-08-03 | — | — | CN | disclosed |